Research Paper in Herbal Chemistry

Review on Nano based herbal face wash powder

Swathisri.S, Naganandhini.K and Radha Palaniswamy,DOI: 10.24214/IJGHC/HC/9/1/00125.

World of beauty revolves around cosmetics. Synthetic cosmetics have now gained the backseat with natural cosmetics are in the top gear now. Herbal cosmetics are in trend which can be synthesized using several herbal plants. These herbal preparations do not cause any side effects on the internal or external parts of the skin. Due to this property, it has gained paramount importance. With the advent of nanoscience, nanoparticles (NP) have gained a predominant place since they have a greater surface area and better effect which has been proved to exhibit potential antimicrobial effect. The present literature focuses on Euphorbia hirta (asthma weed), Senna auriculata (matura tea tree), Camellia sinensis (green tea), Vitex agnus-castus (chaste tree), Cucumis sativus (cucumber), Citrus limon (lemon),  Allium cepa (onion), Borassus flabellifer (palm), Curcuma longa (turmeric), Azadirachta indica (neem), Ocimum basilicum linn (sweet basil) which helps to cure the skin disorders. Formulation and evaluation of herbal face powders using different parameters is an interesting element of cosmetic science and herbal medicine. This review describes some medicinal properties used to treat pimple, acne, dark circle, marks and pigments.">

Evaluation of Some Nutritional Profile of Pineapple(Ananas comosus (L.) merr) Rinds">

K. Asemave; T. Philip Tarhemba & G.O. Obochi,DOI: 10.24214/IJGHC/HC/9/1/02637.

The determination of proximate, vitamins and minerals characterization of the rinds of four varieties of pineapple was carried out in order to add value to the rinds as to reduce agro waste on the environment. The rinds of pineapple used for this work were derived from pineapple fruits (Native Pineapple, Queens Pineapple, MD-2 Pineapple and Smooth Cayene pineapple) coded A, B, C and D respectively. The pineapples were thoroughly washed with water and carefully peeled using stainless steel knife to obtain the rinds. The rinds were chopped into small pieces, spread on the trays and oven dried at 50 OC for 48 h. The dry samples were blended using Chefman 500 W Blender and the blended powders were sieved using 0.5 µm sieve. The fine powders were then packed in sample bottles labeled A, B, C and D respectively. The result obtained from the proximate analysis shows that variety C recorded the highest amount of protein content (6.21±0.10%) and was observed to be insignificantly different (P<0.05) from all the four varieties of the rinds. Rinds of varieties C and D were found to be high in lipids with C (6.47±0.10%) containing the highest amount. At 5% level of significance, lipid content of all the varieties [A (0.41±0.10%), B (0.28±0.02%), C (6.47±0.10%) and D (6.16±0.31%)] were significantly different from each other. Variety B recorded the highest CHO content (83.66±0.03%) follow by A (81.02±0.01%), D (77.17±0.01%) and C (73.04±0.14%) respectively. The CHO content was also significantly (P<0.05) different across the four varieties so also the ash content. Variety A had higher crude fibre content (2.75±0.02%) that was significantly (P<0.05) different from the other varieties [B (1.00±0.00%), C (1.92±0.04%) and D (1.49±0.00%)] - which contained varying amount of crude fibre that were not significantly (P<0.05) different from each other. The result of vitamin content shows that variety D has the highest amount of vitamin A (3.18±0.00 mg/100g) than varieties A, B & C. There were no significant (P<0.05) difference in Vitamin B1, B3 and B6 of the four varieties of the rinds. The result also shows that all the varieties are high in mineral content. Variety B contains the highest amount of Ca (37.45±0.13mg/100g) and Fe (51.46±0.02mg/100g) while variety C was found to be higher in Mg, K, P and Zn. Thus the rinds contain important health promoting nutrients which can be advanced in the formulation of food and drugs products. ">

Role of Shastika Shali Pinda Sweda & Medhya Churna in the Management of Cerebral Palsy">

Anil kumar, Sanjay Gupta, Parul Sharma3, Sapna kumari vishwas, Poonam,DOI: 10.24214/IJGHC/HC/9/1/03842.

Cerebral palsy (CP) a static non-progressive disorder caused by brain insult or injury in the prenatal, perinatal, and postnatal time period, is the major developmental disability affecting normally control motor functions and it has the potential to have an effect on the overall development of a child. The disease is not curable but early intervention with counselling appropriate medication and physiotherapy along with Panchakarma procedures will help to improve their quality of life and give active and self-supporting happy life. There is one very important chapter of Vatavyadhi with good contribution for the causative and management aspect of CP.There are various methods of therapy including Snehana, Swedana, Basti etc. like panchakarma procedure and Medhya,Balya, Rasayana drugs may help at both physical and mental level. For that purpose here Abhyanga with Bala Taila followed by Shashtika Shali Pinda Sweda(SSPS).">

Stability Study of Tila Taila and Murchchit Tila Taila

Dr. Hitaba Gohil and Dr.Pankaj Rupapara,DOI: 10.24214/IJGHC/HC/9/1/04353

: Development of Ayurvedic Pharmaceutical science with it’s and virtue of standardization and quality control, is first requisite of this time to fulfill the increasing demands of this health care system. Sneha kalpana is a well-known and abundantly used form of medicaments in ayurvedic therapeutic multiform of drug administration more it so popular in ayurvedic health care system. Murcchana is a special pharmaceutical procedure by which bad odour, colour of sneha is removed along with amadosha. Real time stability are intended to Show that the drug/oils substance well remain within specification during the retest period or shelf life period if stored under recommended storage conditions in the proposed bulk storage container the main detoration problem in oils and fats are rancidity due to auto oxidation of the unsaturated components. Murcchana is a special pharmaceutical procedure before subjecting the drug to Sneapaka, it is considered as one of the Samskaras of Sneha Murchchana. it may be delicate long shelf life.">

Siravyadha as Ardhachikitsa: A Study Review

Dr. Jayesh S Shivade,DOI: 10.24214/IJGHC/HC/9/1/05463

The rapid modernization in India, fast food culture, stressful and speedy life prevalent in urban areas is spreading its wings in remote villages too. Nowadays human beings are vulnerable to many disorders due to their altered life style and food habits. Considering the importance of rakta in the causation and transmission of various diseases, sushruta has considered rakta as fourth dosa. Dushta rakta is more distressing and common disorder prevalent in present era. It is characterized by severe pain, tenderness, inflammation and burning sensation in the affected area etc. Sedentary lifestyle along with mental stress, consumption of non-vegetarian and highly protein diet, excessive alcohol intake are some of the precipitating factors which causes acute exacerbation of vitiated rakta disorders. By shodhana chikitsa its can be cure and prevented. Raktamokshana, in simple words is the procedure of allowing the blood to bleed for therapeutic purposes. The other panchakarmas eliminates the morbid dosha, while raktamokshana eliminate the vitiated rakta along with rakta, pitta is also likely to be eliminated as both these are interlinked. The utility and significance of rakta mokshana is unique through which number of diseases can be relieved.

Phytochemical Screening and Evaluation of Anti-Bacterial Activity of Peganum harmala leaves and stem extract

Amita, Ram Chandra Beniwal & N. Bhojak;DOI: 10.24214/IJGHC/HC/9/1/06469

The aim of present study was to analyze the phytochemicals present in the extracts of Peganum harmala leaves and to evaluate the antibacterial activity of different extracts. The extract of Peganum harmala leaves was prepared by using Soxhlet extraction protocol. Different solvents i.e. water, alcohol, petroleum ether and micellar medium were used successively to extract different photochemicals. Preliminary phytochemical screening of leaves extract showed the presence of flavonoids, alkaloids, saponins, tannins, glycosides, terpenoids and steroids. The antibacterial activities of extracts were evaluated by disc diffusion method. Antibacterial activity was screened against Escherichia coli, Bascillus subtilis and Staphylococcus aureus. Micellar extract of leaves exhibited the greatest antibacterial activity against Bascillussubtilis.

Quantitative evaluation for foliar pigments, nutrients, flavonoids, polyphenol and antioxidant activity of Gynura procumbens (Lour). Merr. o n different growing seasons

Mohammed Sala Uddin, Fatema Akter and K. M. M. Alam ,DOI: 10.24214/IJGHC/HC/9/1/07080

Quantitative evaluation for foliar pigments, nutrients, flavonoids, polyphenol and antioxidant activities of Gynura procumbens (Lour). Merr. was done on three different growing seasons within a year. A pot culture based experiment was conducted during February, 2017 to January, 2018 at the Botanical Garden of Chittagong University. Maximum foliar photosynthetic pigments, nutrients, polyphenol were observed in monsoon (June-August) and minimum in late monsoon (September-November) respectively. Whilst the highest flavonoids content was determined in the leaf extract of early monsoon (March-May) and the lowest in late monsoon (September-November) respectively. Furthermore, the maximum antioxidant activity was estimated in the leaf extract of late monsoon (September-November) and the lowest in early monsoon (March-May) respectively. The present study concludes that monsoon (June-August) is suitable for efficient photosynthesis, nutrient as well as polyphenol accumulation in Gynura and early monsoon (March-May) is favourable for maximum flavonoid synthesis and late monsoon (September-November) is the right time for harvesting the leaves of Gynura to obtain maximum antioxidant activity for medicinal use.

Effectiveness of Karpooradi Kuzhambu in Chronic Blepharitis

Karthika Rajagopal,DOI: 10.24214/IJGHC/HC/9/1/08195.

Blepharitis is one of the most commonly encountered ophthalmic conditions. It poses a significant challenge to the managing clinician due to its chronic nature and availability of diverse treatment options but lack of scientific evidence for reference. Complete disease elimination is rarely achieved with the modern line of management which include topical antibiotic and weak steroid ointment.In Ayurvedic classics, many treatments are mentioned for netra roga having similar signs and symptoms of chronic Blepharitis. Karpuradi kuzhampu is a rasakriya preparation mentioned in Sahasrayoga which is indicated in netra roga, especially Vartma roga. 20 subjects satisfying the inclusion criteria were taken into the study.The preparatory procedures were vicharana snehapana, virechana, jalaukavacharan and marsha nasya. Anjana was done with Karpuradi kuzhampu and follow up was taken after 1 month, 2 months and 3 months.  Statistical analysis shows that Karpuradi kuzhampu is effective in reducing the signs and symptoms of chronic nonspecific Blepharitis. It is more effective in reducing itching in chronic nonspecific Blepharitis. Karpuradi kuzhampu is not very effective in reducing erythema of lid margin of chronic nonspecific Blepharitis.Hence Ayurvedic method of management may be considered as a very good remedy with respect to chronic Blepharitis.

Determination of the Total Polyphenolic Content and Screening for   Diosmetin in Four Philippine Edible Plants

Lunesa PINZON, John Louie BILLONES and Trecy Jane RICABORDA,DOI: 10.24214/IJGHC/HC/9/1/09604.

: Four Philippine edible plants were analyzed for polyphenols and diosmetin.  They were selected because they have been reported to contain diosmetin which is a non-widespread flavone and the active agent in some venoactive drugs for the treatment of varicose veins, hemorrhoids and other venous diseases. The plants analyzed were Citrofortunella microcarpa, Citrus aurantium Linn., Premna odorata Blanco and Luffa cylindrica Linn. The plant parts used were those that were not generally perceived to have much commercial value. The UV-Vis spectra at 431.5 nm of the DCM-soluble extracts showed the total polyphenolic content, expressed as  quercetin, increases in the following order: P. odorata, L. cylindrica, C. aurantium,  C. microcarpa. The HPLC chromatograms at 348 nm of the DCM-soluble extracts showed the presence diosmetin in all plant extracts. The retention times were: 4.250 mins in the rind of C. aurantium, 4.103 mins in the rind of C. microcarpa, 4.129 mins in the leaves of P. odorata, and 4.297 mins in the leaves of L. cylindrica. The diosmetin content increases in the following order: L. cylindrica, P. odorata, C. aurantium,  C. microcarpa. This study concludes that the rind of the widely cultivated C. microcarpa, which are generally thrown as garbage, can be a very good source of polyphenolics, particularly the non-widespread, venoactive and chemopreventive diosmetin. This abundant, but seemingly useless, material can be commercialized as dietary supplement.